Formation of Cartilage

Formation of Cartilage

Cartilage, Chondroblasts, Collagen, Chondrocytes

This animation describes the process of cartilage formation starting with separation from the mesenchymal tissue to the formation of an isogenous cell group via mitosis.

Developing cartilage is separated from the surrounding mesenchymal tissue by a fibrous layer of cells, the perichondrium. In appositional growth, cells of the inner chondrogenic layer of the perichondrium differentiate into chondroblasts and migrate inward. Ongoing growth occurs interstitially, as chondroblasts within the cartilage secrete type 2 collagen precursors and other components of the extracellular matrix. The zone surrounding each chondroblast is known as the territorial matrix. Chondroblasts divide by mitosis and the daughter cells remain within the same space, or lacuna, forming an isogenous cell group. Each isogenous group of mature chondrocytes and its territorial matrix is surrounded by the wider interterritorial matrix.

To learn more about this topic please contact Professor Hysell Oviedo: hoviedo@ccny.cuny.edu

02/28/2014

Credits: Ching-Jung Chen, Abraham Kierszenbaum, Robert Levy, Lena Marvin, Jazmine Rogers, Aleksandr Vinkler

Formation of Cartilage by City College of New York Digital Scholarship Services is licensed under a Creative Commons Attribution 4.0 International License.

MPEG-4

English

animation

ANI001