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This animation shows how electrical impulses generated by neurons (action potentials) lead to the expression of C-fos by the cell nucleus. C-fos is thus considered an immediate early gene product of recent neural activity. It is widely used in…

Brief animation showing how a primary and secondary antibody are used to detect C-fos, an immediate early gene transcribed as a result of recent neural activity. To see why and how C-fos is made please watch the companion video Cfos neural activity